All Hokie, All the Time. Period. Presented by

The Lounge Board

Hokie360

Joined: 08/26/2006 Posts: 17911
Likes: 7206


Link to actual press release (with more data)


Previous link was just the Yahoo finance story. Actual press release contains more data.

In an ongoing U.S. Phase 1/2 placebo-controlled, observer-blinded clinical trial, nucleoside-modified messenger RNA vaccine candidate (BNT162b1) expressing the SARS-CoV-2 receptor binding domain (RBD) is being evaluated in 45 subjects
At day 28 (7 days after dose 2), all subjects who received 10 or 30 mg of BNT162b1 had significantly elevated RBD-binding IgG antibodies with geometric mean concentrations (GMCs) of 4,813 and 27,872 units/ml which are 8- and 46.3-times, respectively, the GMC of 602 units/ml in a panel of 38 sera of convalescent patients who had contracted SARS-CoV-2
At day 28 (7 days after dose 2), all subjects who received 10 or 30 mg of BNT162b1 had SARS-CoV-2 neutralizing antibodies with geometric mean titers (GMTs) of 168 and 267, which are 1.8- and 2.8-times, respectively, the GMT of the convalescent serum panel
Local reactions and systemic events after immunization with 10 µg and 30 µg of BNT162b1 were dose-dependent, generally mild to moderate, and transient. No serious adverse events were reported
Further data from the ongoing Phase 1/2 clinical trial of four vaccine candidates will enable selection of a lead candidate and dose level for a large, global Phase 2b/3 safety and efficacy study that may begin as early as July 2020
Efforts to manufacture the leading candidates, at risk, are gearing up. In case the safety and efficacy study is successful, and the vaccine receives regulatory approval, the companies are expecting to manufacture up to 100 million doses by the end of 2020 and potentially more than 1.2 billion doses by the end of 2021

(In response to this post by HokieAl)

Link: PFIZER AND BIONTECH ANNOUNCE EARLY POSITIVE DATA FROM AN ONGOING PHASE 1/2 STUDY


Posted: 07/01/2020 at 09:52AM



+0

Insert a Link

Enter the title of the link here:


Enter the full web address of the link here -- include the "http://" part:


Current Thread:
  There are different ways that vaccines work -- Hokie Chris 07/02/2020 09:27AM
  Yes -- VTSnake 07/01/2020 2:06PM
  Yep. Herd immunity requires herd infection ** -- Beerman 07/01/2020 11:15AM
  Personally, I prefer to be in the uninfected herd. ** -- PhotoHokieNC 07/01/2020 11:27AM
  Don't we all ** -- Beerman 07/01/2020 11:33AM
  This suggest's no. It can be a combo & vax(LINK) -- 48zip 07/01/2020 10:52AM
  That's some good news ** -- HokieR 07/01/2020 10:27AM
  That’s where iBio comes in. ** -- BobG 07/01/2020 10:20AM
  I've been to Pfizer's vaccine plant -- Hokie Chris 07/01/2020 10:15AM
  Link to actual press release (with more data) -- Hokie360 07/01/2020 09:52AM
  Get ‘em Al. No room for optimism around here. ** -- vthokieq 07/01/2020 09:51AM
  CNBC needs to lose Jim Cramer. He has lost it. His -- GreenvilleVT 07/01/2020 09:30AM
  Hopefully there is no lime shortage. ** -- GreenvilleVT 07/01/2020 09:51AM

Tech Sideline is Presented By:

Our Sponsors

vm307